Periodic paralysis
HUMAN DISEASE
Familial periodic paralysis; Periodic Paralysis; Paralyses, familial periodic; Periodic Paralyses; Periodic paralyses; Familial Periodic Paralysis; Familial periodic paralyses
Periodic paralysis is a group of rare genetic diseases that lead to weakness or paralysis from common triggers such as cold, heat, high carbohydrate meals, not eating, stress or excitement and physical activity of any kind. The underlying mechanism of these diseases are malfunctions in the ion channels in skeletal muscle cell membranes that allow electrically charged ions to leak in or out of the muscle cell, causing the cell to depolarize and become unable to move.